Uveitis MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]

Overview

There are no diagnostic MRI findings associated with uveitis. The presence of certain MRI findings, in the presence of uveitis, may be suggestive of specific underlying causes such as sarcoidosis, multiple sclerosis, Behcet's disease, syphilis, and joint abnormalities in seronegative spondyloarthropathies.[1][2][3][4][5]

MRI

There are no diagnostic MRI findings associated with uveitis. The presence of certain MRI findings, in the presence of uveitis, may be suggestive of specific underlying causes such as:

Sarcoidosis

The following MRI findings are suggestive of neurosarcoidosis:[1]

  • Hypointense lesions adjacent to grey matter
  • Homogeneous enhancement and meningeal thickening (in meningeal involvement)

Multiple Sclerosis

The following MRI findings are suggestive of multiple sclerosis:[2]

  • Hypointense periventricular, juxtacortical, or infratentorial lesions on T1 imaging
  • Hyperintense periventricular, juxtacortical, or infratentorial lesions on T2 imaging

Behcet's Disease

The following MRI findings are suggestive of neurological manifestations of Behcet's disease:[3]

Neurosyphilis

The following MRI findings are suggestive of neurological manifestations of syphilis:[4]

  • Longitudinal hypointense T2 weighted images in the dorsal column of the spinal cord in tabes dorsalis

Seronegative Spondyloarthropathies

The following MRI findings are suggestive of joint abnormalities in seronegative spondyloarthropathies:[5]

  • Synovial enhancement
  • Hyperintense T2 signal
  • Bone erosions and subchondral bone changes

References

  1. 1.0 1.1 Smith JK, Matheus MG, Castillo M (2004). "Imaging manifestations of neurosarcoidosis". AJR Am J Roentgenol. 182 (2): 289–95. doi:10.2214/ajr.182.2.1820289. PMID 14736648.
  2. 2.0 2.1 Lövblad KO, Anzalone N, Dörfler A, Essig M, Hurwitz B, Kappos L; et al. (2010). "MR imaging in multiple sclerosis: review and recommendations for current practice". AJNR Am J Neuroradiol. 31 (6): 983–9. doi:10.3174/ajnr.A1906. PMID 20019103.
  3. 3.0 3.1 Hegde AN, Mohan S, Lath N, Lim CC (2011). "Differential diagnosis for bilateral abnormalities of the basal ganglia and thalamus". Radiographics. 31 (1): 5–30. doi:10.1148/rg.311105041. PMID 21257930.
  4. 4.0 4.1 Pandey S (2011). "Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis". J Spinal Cord Med. 34 (6): 609–11. doi:10.1179/2045772311Y.0000000041. PMC 3237288. PMID 22330117.
  5. 5.0 5.1 Jacobson JA, Girish G, Jiang Y, Resnick D (2008). "Radiographic evaluation of arthritis: inflammatory conditions". Radiology. 248 (2): 378–89. doi:10.1148/radiol.2482062110. PMID 18641245.

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