Tuaminoheptane

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Template:Chembox ECNumberTemplate:Chembox E numberTemplate:Chembox UNNumberTemplate:Chembox GHSPictogramsTemplate:Chembox GHSSignalWordTemplate:Chembox HPhrasesTemplate:Chembox PPhrasesTemplate:Chembox Lethal amounts (set)
Tuaminoheptane
Skeletal formula of tuaminoheptane
Names
IUPAC name
Heptan-2-amine[1]
Identifiers
3D model (JSmol)
Beilstein Reference 635676, 4652352 R, 1719086 S
ChEMBL
ChemSpider
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KEGG
MeSH tuamine
RTECS number MQ5425000
UNII
Properties
C7H17N
Molar mass 115.22 g·mol−1
Appearance Colourless liquid
Density 0.766 g/mL
Boiling point
log P 2.429
Refractive index (nD) 1.418–1.419
Hazards
Flash point {{{value}}}
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tuaminoheptane (or tuamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.[2] However, it can cause skin irritation,[3] which limits its usefulness as a nasal decongestant. Oral preparations were once available, but are no longer produced. Side effects associated with the use of tuaminoheptane can include shortness of breath, tachycardia and hypertension.

Tuaminoheptane is on the 2011 list of prohibited substances published by the World Anti-Doping Agency.

See also

References

  1. "tuamine - Compound Summary". USA: National Center for Biotechnology Information. 25 March 2005. Identification and Related Records. Retrieved 31 May 2012.
  2. Delicado, E. G.; Fideu, M. D.; Miras-Portugal, M. T.; Pourrias, B.; Aunis, D. (1990). "Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells". Biochemical Pharmacology. 40 (4): 821–825. doi:10.1016/0006-2952(90)90322-C. PMID 2386550.
  3. Raoux, M.; Colomban, C.; Delmas, P.; Crest, M. (2007). "The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes". Molecular Pharmacology. 71 (6): 1685–1694. doi:10.1124/mol.106.033324. PMID 17384225.

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