Transition nuclear protein

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Transition nuclear proteins (TNPs) are proteins that are involved in the packaging of sperm nuclear DNA during spermiogenesis. They take the place of histones associated with the sperm DNA, and are subsequently themselves replaced by protamines.

See also


  • Meistrich ML, Mohapatra B, Shirley CR, Zhao M. 2003. Role of transition nuclear proteins in spermiogenesis. Chromosoma 111:483-488.