TSPO (protein)

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translocator protein (18kDa)
Identifiers
SymbolTSPO
Alt. symbolsBZRP
Entrez706
HUGO1158
OMIM109610
RefSeqNM_007311
UniProtP30536
Other data
LocusChr. 22 q13.3

TSPO (Translocator Protein), also known as the peripheral benzodiazepine receptor (PBR), is a 18 kDa mitochondrial membrane protein.[1] Among its many functions are regulation of steroidogenesis and apoptosis.[2]

References

  1. Papadopoulos V, Baraldi M, Guilarte TR, Knudsen TB, Lacapere JJ, Lindemann P, Norenberg MD, Nutt D, Weizman A, Zhang MR, Gavish M (2006). "Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function". Trends Pharmacol Sci. 27 (8): 402–9. PMID 16822554.
  2. Casellas P, Galiegue S, Basile AS (2002). "Peripheral benzodiazepine receptors and mitochondrial function". Neurochem Int. 40 (6): 475–86. PMID 11850104.

External links

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