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T cell receptor delta locus
Symbols TRD@ ; TCRD; TRD
External IDs Template:OMIM5
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

T cell receptor delta locus, also known as TRD@, is a human gene.[1]


  1. "Entrez Gene: TRD@ T cell receptor delta locus".

Further reading

  • Chien YH, Iwashima M, Kaplan KB; et al. (1987). "A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation". Nature. 327 (6124): 677–82. doi:10.1038/327677a0. PMID 2439914.
  • Hayes SM, Shores EW, Love PE (2003). "An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors". Immunol. Rev. 191: 28–37. PMID 12614349.
  • Guglielmi P, Davi F, d'Auriol L; et al. (1988). "Use of a variable alpha region to create a functional T-cell receptor delta chain". Proc. Natl. Acad. Sci. U.S.A. 85 (15): 5634–8. PMID 2456576.
  • Hochstenbach F, Brenner MB (1989). "T-cell receptor delta-chain can substitute for alpha to form a beta delta heterodimer". Nature. 340 (6234): 562–5. doi:10.1038/340562a0. PMID 2528071.
  • Dyer MJ (1989). "T-cell receptor delta/alpha rearrangements in lymphoid neoplasms". Blood. 74 (3): 1073–83. PMID 2546634.
  • Griesinger F, Greenberg JM, Kersey JH (1989). "T cell receptor gamma and delta rearrangements in hematologic malignancies. Relationship to lymphoid differentiation". J. Clin. Invest. 84 (2): 506–16. PMID 2547833.
  • Loh EY, Lanier LL, Turck CW; et al. (1988). "Identification and sequence of a fourth human T cell antigen receptor chain". Nature. 330 (6148): 569–72. doi:10.1038/330569a0. PMID 2825032.
  • Bartkowiak J, Kulczyck-Wojdala D, Blonski JZ, Robak T (2002). "Molecular diversity of gammadelta T cells in peripheral blood from patients with B-cell chronic lymphocytic leukaemia". Neoplasma. 49 (2): 86–90. PMID 12088111.
  • Oyoshi MK, Nagata H, Kimura N; et al. (2003). "Preferential expansion of Vgamma9-JgammaP/Vdelta2-Jdelta3 gammadelta T cells in nasal T-cell lymphoma and chronic active Epstein-Barr virus infection". Am. J. Pathol. 162 (5): 1629–38. PMID 12707047.
  • Krejci O, Prouzova Z, Horvath O; et al. (2003). "Cutting edge: TCR delta gene is frequently rearranged in adult B lymphocytes". J. Immunol. 171 (2): 524–7. PMID 12847212.
  • van Hagen PM, Hooijkaas H, Vd Beemd MW; et al. (2003). "T-gammadelta receptor restriction in peripheral lymphocytes of patients with Behçet's disease". Adv. Exp. Med. Biol. 528: 267–8. PMID 12918704.
  • Szczepanski T, van der Velden VH, Hoogeveen PG; et al. (2004). "Vdelta2-Jalpha rearrangements are frequent in precursor-B-acute lymphoblastic leukemia but rare in normal lymphoid cells". Blood. 103 (10): 3798–804. doi:10.1182/blood-2003-08-2952. PMID 14656882.
  • De Rosa SC, Andrus JP, Perfetto SP; et al. (2004). "Ontogeny of gamma delta T cells in humans". J. Immunol. 172 (3): 1637–45. PMID 14734745.
  • Fronková E, Krejcí O, Kalina T; et al. (2005). "Lymphoid differentiation pathways can be traced by TCR delta rearrangements". J. Immunol. 175 (4): 2495–500. PMID 16081821.
  • Chauhan SK, Tripathy NK, Sinha N, Nityanand S (2006). "T-cell receptor repertoire of circulating gamma delta T-cells in Takayasu's arteritis". Clin. Immunol. 118 (2–3): 243–9. doi:10.1016/j.clim.2005.10.010. PMID 16307908.
  • Joachims ML, Chain JL, Hooker SW; et al. (2006). "Human alpha beta and gamma delta thymocyte development: TCR gene rearrangements, intracellular TCR beta expression, and gamma delta developmental potential--differences between men and mice". J. Immunol. 176 (3): 1543–52. PMID 16424183.
  • Karrman K, Andersson A, Björgvinsdóttir H; et al. (2006). "Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia". Eur. J. Haematol. 77 (1): 27–34. doi:10.1111/j.0902-4441.2006.t01-1-EJH2553.x. PMID 16548914.
  • Touvrey C, Borel E, Marche PN; et al. (2006). "Gene-specific signal joint modifications during V(D)J recombination of TCRAD locus genes in murine and human thymocytes". Immunobiology. 211 (9): 741–51. doi:10.1016/j.imbio.2006.04.001. PMID 17015149.

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