TMEM242

Jump to navigation Jump to search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Transmembrane protein 242 (TMEM242) is a protein that in humans is encoded by the TMEM242 gene.[1]

This protein contains a DUF1358 domain (Domain of Unknown Function 1358).[2]

Domain

The TMEM242 protein has a conserved domain of unknown function pfam 07096, DUF 1358., which covers the first 121 aa of the protein. This domain is conserved in eukaryotes.

Associated Proteins

Several predicted interacting proteins and functional sites on the protein have been identified. One of the predicted interacting protein is MAP2K1IP1, which is a scaffold protein.[3] This protein is known to be involved in the MAP Kinase pathway. The MAP Kinase pathway is associated with the Alzheimer's pathway through a protein called Tau or MAPT. Excessive phosphorylation of this protein leads to aggregation of neurons which can cause Alzheimer's disease.

References

  1. "Entrez Gene: chromosome 6 open reading frame 35".
  2. "Pfam Family: DUF1358 (PF07096)". Pfam. Archived from the original on 2012-08-01.
  3. C6orf35 protein (Homo sapiens) - STRING interaction network

External links

Further reading