Sodium picosulfate

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Sodium picosulfate
File:Sodium picosulfate.svg
Clinical data
Routes of
ATC code
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
Molar mass481.409 g/mol

Sodium picosulfate (INN, also known as sodium picosulphate) is a contact laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Dulcolax, Laxoberal, Picolax, Guttalax and several others.

Side effects

The most common side effects of picosulfate are abdominal cramps and diarrhea.

The use of sodium picosulfate has also been associated with certain electrolyte disturbances, such as hyponatremia and hypokalemia.[1]


  1. ADRAC (2002). "Electrolyte disturbances with sodium picosulfate bowel cleansing products". Aust Adv Drug React Bull. 21 (1). Unknown parameter |month= ignored (help) Free full text from the Australian Therapeutic Goods Administration