Sideroblastic anemia surgery

Sideroblastic anemia Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.

Overview

In severe cases, bone marrow transplant is the only option with limited information about the success rate.

Surgery

• Bone marrow transplantation

• Liver transplantation

Indications

• Surgery is not the first-line treatment option for patients with sideroblastic anemia.
• The indications for surgery are:
  • Young patients with congenital sideroblastic anemia, not responsive to pyridoxine
  • Transfusion dependent patients
  • Liver cirrhosis
  • Iron overload refractory to iron chelation therapy
  • Iron overload refractory to phlebotomy

Contraindications

• Patients with organ damage from secondary hemochromatosis
• Poor surgical candidacy