Sickle-cell disease risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]

Overview

The most potent risk factor in the development of sickle-cell disease is race.

Risk Factors

Common Risk Factors

  • Common risk factors in the development of sickle-cell disease include:[1][2]
    • Africans
    • African Americans
    • Indians
    • Mediterranean descent
    • Geographic location

References

  1. Makani J, Ofori-Acquah SF, Nnodu O, Wonkam A, Ohene-Frempong K (2013). "Sickle cell disease: new opportunities and challenges in Africa". ScientificWorldJournal. 2013: 193252. doi:10.1155/2013/193252. PMC 3988892. PMID 25143960.
  2. Grosse SD, Odame I, Atrash HK, Amendah DD, Piel FB, Williams TN (December 2011). "Sickle cell disease in Africa: a neglected cause of early childhood mortality". Am J Prev Med. 41 (6 Suppl 4): S398–405. doi:10.1016/j.amepre.2011.09.013. PMC 3708126. PMID 22099364.