Sarcoma botryoides surgery
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Sarcoma botryoides, also known as embryonal rhabdomyosarcoma, is a type of rhabdomyosarcoma in the vagina of young girls, typically younger than 8. The name comes from the gross appearance of "grape bunches" (botryoid in Greek).
Surgery
The disease used to be uniformly fatal, with a 5-year survival rate between 10 to 35% (Piver and Rose, 1988)[1]. As a result, treatment was radical surgery[2] [3]. New multidrug chemotherapy regimens with or without radiation therapy are now used in combination with less radical surgery with good results, although outcome data are not yet available (Rotmensch and Yamada, 2003)[4][5].
References
- ↑ Piver M, Rose P (1988). "Long-term follow-up and complications of infants with vulvovaginal embryonal rhabdomyosarcoma treated with surgery, radiation therapy, and chemotherapy". Obstet Gynecol. 71 (3 Pt 2): 435–7. PMID 3347430.
- ↑ Hilgers R (1975). "Pelvic exenteration for vaginal embryonal rhabdomyosarcoma: a review". Obstet Gynecol. 45 (2): 175–80. PMID 1090863.
- ↑ Rahaman, J and Cohen, CJ. Gynecologic Sarcomas. in Holland-Frei Cancer Medicine - 6th Ed. Kufe, DW et al editors. BC Decker Inc, Hamilton, Ontario, 2003.
- ↑ Rotmensch, J and Yamada, SD. Neoplasms of the Vulva and Vagina. in Holland-Frei Cancer Medicine - 6th Ed. Kufe, DW et al editors. BC Decker Inc, Hamilton, Ontario, 2003
- ↑ Reynolds E, Logani S, Moller K, Horowitz I (2006). "Embryonal rhabdomyosarcoma of the uterus in a postmenopausal woman. Case report and review of the literature". Gynecol Oncol. 103 (2): 736–9. PMID 16684558.