Sandbox: maria experimental sandbox


Secondary bone tumors: classification Adapted from Greenspan A et al. 2006 ^[1]

Tumor matrix		Tumor location
Osteolytic	Renal cell cancer Melanoma Multiple myeloma Non-small cell lung cancer Thyroid cancer Non-Hodgkin lymphoma Langerhans cell histiocytosis	Skull	Breast cancer Lung cancer Melanoma Prostate cancer Thyroid cancer (usually follicular) Renal cell cancer Lymphoma Leukaemia Multiple myeloma
Osteoblastic	Prostate cancer Carcinoid syndrome Small cell lung cancer Hodgkin lymphoma Medulloblastoma	Vertebral	Breast cancer Lung cancer Prostate cancer Lymphoma Renal cell carcinoma Gastrointestinal tract malignancies Melanoma
Mixed	Breast cancer Gastrointestinal cancers Squamous cancers (at most primary sites)	Distal appendicular	Lung cancer Breast cancer Renal cell cancer Prostate cancer
Other types ( "Blow out" and "Cookie type")	Renal cell carcinoma Thyroid cancer Hepatocellular carinoma Bronchogenic carcinoma	Distal appendicular


Bone or cartilage mass classification Adapted from ICD-10/WHO (9180–9269)^[2]

Osteogenic tumors: bone-forming tumors	Cartilage tumors: cartilage-forming tumors	Fibrogenic tumors	Cystic tumors	Others ( hematopoietic, notochordal, neuroectodermal)
Histological Type
Osteoid osteoma Osteoblastoma Osteoma Osteosarcoma	Osteochondroma Chondroblastoma Enchondroma Chondromyxoid fibroma	Desmoplastic fibroma Fibrous dysplasia Ossyifing fibroma Non-ossifying fibroma	Unicameral bone cyst Aneurysmal bone cyst	Giant cell tumor Adamantimoma Eosinophilic granuloma Ewing sarcoma Metastases
Epiphysis		Diaphysis	Metaphysis
Tumor Location
Chondroblastoma Giant cell tumor Intraosseous ganglion Chondrosarcoma Metastases Ewing's sarcoma				Eosinophilic granuloma Ewing sarcoma Myeloma Metastases Adamantimoma Ossyfing fibroma Enchondroma	Osteosarcoma Chondromyxoid fibroma Unicameral bone cyst Osteoid osteoma Metastases
Benign			Malignant
Tumor Nature
Osteoid osteoma Enchondroma Chondromyxoid fibroma Ossifying fibroma Osteoblastoma Unicameral bone cyst Aneursymal bone cyst Giant cell tumor Osteochondroma			Osteosarcoma Ewing sarcoma Chondrosarcoma Fibrosarcoma Malignant fibrous histiocytoma Plasma cell myeloma Metastases

Bone or cartilage mass classification Adapted from ICD-10/WHO (9180–9269) ^[2]
Location	Origin	Type of tumor
Diaphysis	Myeloid	Multiple myeloma
	Epithelial	Adamantinoma
	PNET/Ewing family	Ewing's sarcoma
Metaphysis	Osteoblast	Osteoid osteoma
		Osteoblastoma
		Osteoma/osteosarcoma
	Chondroblast	Chondroma/ecchondroma/enchondroma
		Enchondromatosis
		Chondrosarcoma
		Osteochondroma
		Chondromyxoid fibroma
	Fibrous	Ossifying fibroma
	Fibrous	Fibrosarcoma
Epiphysis	Chondroblast	Chondroblastoma
Epiphysis	Myeloid	Giant-cell tumor of bone
Other/ungrouped	Notochord	Chordoma

↑ Greenspan A, Jundt G, Remagen W. Differential diagnosis in orthopaedic oncology. Philadelphia : Lippincott Williams & Wilkins, c2007. (2006) ISBN:0781779308
↑ ^2.0 ^2.1 Miller TT (2008). "Bone tumors and tumorlike conditions: analysis with conventional radiography". Radiology. 246 (3): 662–74. doi:10.1148/radiol.2463061038. PMID 18223119.

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