Sandbox/WCT 1
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Symptoms Related to Tumor Growth in the Thorax
Constitutional Symptoms
Symptoms Related to Paraneoplastic Syndrome
Symptoms Related to the Distant Spread of the Tumor
- Hoarseness (involvement of the recurrent laryngeal nerve)[3]
- Dyspnea (one of the causes is the involvement of the phrenic nerve and subsequent elevation of the hemi-diaphragm)[3]
- Pain, muscle wasting, or change in the skin temperature in areas corresponding to C8, T2 to T4 (involvement of the brachial plexus)[3]
- Chest pain (one of the causes is the involvement of the chest wall)[3]
- Pleuritic chest pain[3]
- Horner syndrome manifested by unilateral miosis, ptosis and anhydrosis (involvement of the sympathetic trunk)[3]
- Arrhythmia (involvement of the pericardium)[3]
- Cardiac tamponade manifested by chest pain, altered mental status, cold extremities, peripheral cyanosis (involvement of the pericardium)[3]
- Dysphagia (compression of the esophagus)[3]
- Superior vena cava syndrome manifested by dyspnea, headache, and swelling of the face, neck, trunk, and arms[3]
Uncommon Symptoms
- Abdominal discomfort due to bilateral adrenal mass[4]
- Facial nerve palsy due to metastasis to the facial nerve[5]
- ↑ 1.0 1.1 1.2 1.3 1.4 van Meerbeeck JP, Fennell DA, De Ruysscher DK (2011). "Small-cell lung cancer". Lancet. 378 (9804): 1741–55. doi:10.1016/S0140-6736(11)60165-7. PMID 21565397.
- ↑ Beckles MA, Spiro SG, Colice GL, Rudd RM (2003). "Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes". Chest. 123 (1 Suppl): 97S–104S. PMID 12527569.
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 Spiro SG, Gould MK, Colice GL, American College of Chest Physicians (2007). "Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes: ACCP evidenced-based clinical practice guidelines (2nd edition)". Chest. 132 (3 Suppl): 149S–160S. doi:10.1378/chest.07-1358. PMID 17873166.
- ↑ Singh N, Madan K, Aggarwal AN, Das A (2013). "Symptomatic large bilateral adrenal metastases at presentation in small-cell lung cancer: a case report and review of the literature". J Thorac Dis. 5 (3): E83–6. doi:10.3978/j.issn.2072-1439.2011.09.05. PMC 3698258. PMID 23825789.
- ↑ Yildiz O, Buyuktas D, Ekiz E, Selcukbiricik F, Papila I, Papila C (2011). "Facial nerve palsy: an unusual presenting feature of small cell lung cancer". Case Rep Oncol. 4 (1): 35–8. doi:10.1159/000324182. PMC 3082487. PMID 21526004.