Salivary gland tumor fine-needle aspiration biopsy (FNAB)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Biopsy of the tumor tissue is diagnostic of salivary gland tumor.[1][2] Histopathological findings on biopsy can be found here.

Fine-needle aspiration biopsy

A biopsy is required to establish a definitive diagnosis of a salivary gland tumor and to plan therapy. A preoperative biopsy (either fine needle aspiration cytology or ultrasound guided core needle) can be performed to avoid operating on a nonsurgically-managed disease process and to aid in surgical planning, if anatomically feasible. However, a preoperative histologic diagnosis is not always possible.[2][1]

  • Fine needle aspiration (FNA)
    • Fine needle aspiration (FNA) provides a highly accurate assessment of the cells for diagnosis. It helps to determine whether a lump is a salivary gland tumor, an infection or another type of cancer. Fine needle aspiration (FNA) biopsy: The removal of tissue or fluid using a thin needle. A pathologist views the tissue or fluid under a microscope to look for cancer cells. In order to make a final diagnosis of salivary gland cancer a sample of tissue from the area is taken and examined under a microscope to look for signs of cancer.
    • Ultrasound guided needle biopsy. During ultrasound-guided needle biopsy, the images produced by an ultrasound is used to guide a needle into the tumor.
  • Incisional biopsy
    • A small piece of the lump is removed and looked at under a microscope to see if cancer cells are present. It may be done if the FNA does not provide enough tissue for diagnosis, but is not done very often. If doctors cannot confirm the diagnosis of a salivary gland tumor even after imaging tests or FNA, surgery is done and the tumor is tested for cancer cells after it is surgically removed.

References

  1. 1.0 1.1 Salivary gland cancer. National cancer institute(2015) http://www.cancer.gov/types/head-and-neck/hp/salivary-gland-treatment-pdq#link/_410_toc Accessed on November 8, 2015
  2. 2.0 2.1 Salivary gland cancer. Wikipedia(2015) https://en.wikipedia.org/wiki/Salivary_gland_neoplasm Accessed on November 8, 2015

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