Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene .[ 1] [ 2]
Function
SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM][ 2]
Interactions
SUDS3 has been shown to interact with HDAC1 ,[ 1] [ 3] Host cell factor C1 ,[ 4] SIN3B [ 1] SIN3A .[ 1] [ 3]
References
↑ 1.0 1.1 1.2 1.3 Alland L, David G, Shen-Li H, Potes J, Muhle R, Lee HC, Hou H, Chen K, DePinho RA (April 2002). "Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex" . Molecular and Cellular Biology . 22 (8): 2743–50. doi :10.1128/MCB.22.8.2743-2750.2002 . PMC 133736 PMID 11909966 . ↑ 2.0 2.1 "Entrez Gene: SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)" .↑ 3.0 3.1 Fleischer TC, Yun UJ, Ayer DE (May 2003). "Identification and characterization of three new components of the mSin3A corepressor complex" . Molecular and Cellular Biology . 23 (10): 3456–67. doi :10.1128/MCB.23.10.3456-3467.2003 . PMC 164750 PMID 12724404 . ↑ Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W (April 2003). "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1" . Genes & Development . 17 (7): 896–911. doi :10.1101/gad.252103 . PMC 196026 PMID 12670868 .
Further reading
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 . PMID 17081983 . Fleischer TC, Yun UJ, Ayer DE (May 2003). "Identification and characterization of three new components of the mSin3A corepressor complex" . Molecular and Cellular Biology . 23 (10): 3456–67. doi :10.1128/MCB.23.10.3456-3467.2003 . PMC 164750 PMID 12724404 . Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W (April 2003). "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1" . Genes & Development . 17 (7): 896–911. doi :10.1101/gad.252103 . PMC 196026 PMID 12670868 . Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O (December 2000). "Characterization of long cDNA clones from human adult spleen". DNA Research . 7 (6): 357–66. doi :10.1093/dnares/7.6.357 . PMID 11214971 .
