Rhabdomyoma biopsy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

Rhabdomyoma is a benign tumor of striated muscle. Rhabdomyomas are rare and can be classified into cardiac type and extracardiac type. The most common primary benign pediatric tumor of the heart is cardiac rhabdomyoma which can be seen mainly in fetal life and children. Cardiac rhabdomyoma is seen almost always in the pediatric age group and is associated with tuberous sclerosis, neurofibromatosis, and sebaceous adenomas. Extracardiac rhabdomyoma can be divided into three groups (adult, fetal, and genital types) with distinct clinical and morphological differences.

Biopsy

  • On biopsy specimen round or polypoid mass in the region of the neck are characteristic findings of adult rhabdomyoma.
    • Round or lobulated, well-circumscribed masses which can be up to 10 cm in diameter.[1]
    • Isolated or multiple.
    • Solid tan-white homogeneous consistency, often watery and glistening on their cut surface.
    • Infrequently, calcification and hemorrhage.

References

  1. Kassop D, Donovan MS, Cheezum MK, Nguyen BT, Gambill NB, Blankstein R, Villines TC (2014). "Cardiac Masses on Cardiac CT: A Review". Curr Cardiovasc Imaging Rep. 7: 9281. doi:10.1007/s12410-014-9281-1. PMC 4090749. PMID 25018846.

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