Reversible inhibitor of monoamine oxidase A
Reversible inhibitors of monoamine oxidase type-A (RIMAs) are a family of psychiatric drugs and natural compounds that inhibit monoamine oxidase, temporarily and reversibly. They are mostly used for alleviating depression and dysthymia.
These drugs, a subset of monoamine oxidase inhibitors (MAOIs), inhibit only isoenzyme A and are reversible. Isoenzyme B remains free to metabolize tyramine contained in some foods, so they are safer and may not require a special diet.
Because their action is short-lived and selective, they have a better safety profile than the older MAOI drugs (monoamine oxidase inhibitors). A special diet does not need to be so strictly adhered to, although eating excessively large amounts of tyramine-containing foods is not advisable.
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