RARRES2

Retinoic acid receptor responder (tazarotene induced) 2
Identifiers
Symbols	RARRES2 ; HP10433; TIG2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2167
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE RARRES2 209496 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Retinoic acid receptor responder (tazarotene induced) 2, also known as RARRES2, is a human gene.

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES2 is thought to act as a cell surface receptor.

Further reading

• Duvic M, Nagpal S, Asano AT, Chandraratna RA (1997). "Molecular mechanisms of tazarotene action in psoriasis". J. Am. Acad. Dermatol. 37 (2 Pt 3): S18–24. PMID 9270552.CS1 maint: Multiple names: authors list (link)
• Nagpal S, Patel S, Jacobe H; et al. (1997). "Tazarotene-induced gene 2 (TIG2), a novel retinoid-responsive gene in skin". J. Invest. Dermatol. 109 (1): 91–5. PMID 9204961.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yokoyama-Kobayashi M, Yamaguchi T, Sekine S, Kato S (1999). "Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank". Gene. 228 (1–2): 161–7. PMID 10072769.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Scherer SW, Cheung J, MacDonald JR; et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hillier LW, Fulton RS, Fulton LA; et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wittamer V, Franssen JD, Vulcano M; et al. (2003). "Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids". J. Exp. Med. 198 (7): 977–85. doi:10.1084/jem.20030382. PMID 14530373.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vermi W, Riboldi E, Wittamer V; et al. (2005). "Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin". J. Exp. Med. 201 (4): 509–15. doi:10.1084/jem.20041310. PMID 15728234.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wittamer V, Bondue B, Guillabert A; et al. (2005). "Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity". J. Immunol. 175 (1): 487–93. PMID 15972683.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zabel BA, Allen SJ, Kulig P; et al. (2005). "Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades". J. Biol. Chem. 280 (41): 34661–6. doi:10.1074/jbc.M504868200. PMID 16096270.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Goralski KB, McCarthy TC, Hanniman EA; et al. (2007). "Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism". J. Biol. Chem. 282 (38): 28175–88. doi:10.1074/jbc.M700793200. PMID 17635925.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Roh SG, Song SH, Choi KC; et al. (2007). "Chemerin--a new adipokine that modulates adipogenesis via its own receptor". Biochem. Biophys. Res. Commun. 362 (4): 1013–8. doi:10.1016/j.bbrc.2007.08.104. PMID 17767914.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)