R-GCVP regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: Rituximab-Gemcitabine-Cyclophosphamide-Vincristine-Prednisone regimen

Overview

R-GCVP regimen refers to a regimen consisting of rituximab, gemcitabine, cyclophosphamide, vincristine (Oncovin), and prednisone used to treat both indolent and aggressive forms of diffuse large B-cell lymphoma.[1]

Regimen

RRituximab

GGemcitabine

CCyclophosphamide

VVincristine (Oncovin)

PPrednisone

Indications

References

  1. 1.0 1.1 Fields PA, Townsend W, Webb A, Counsell N, Pocock C, Smith P; et al. (2014). "De novo treatment of diffuse large B-cell lymphoma with rituximab, cyclophosphamide, vincristine, gemcitabine, and prednisolone in patients with cardiac comorbidity: a United Kingdom National Cancer Research Institute trial". J Clin Oncol. 32 (4): 282–7. doi:10.1200/JCO.2013.49.7586. PMID 24220559.