Pulmonary amyloidosis overview

Pulmonary amyloidosis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Amyloidosis limited to the respiratory tract is uncommon.

• Pulmonary amyloidosis occurs in three histopathologic types
  • Focal deposits in the tracheobronchial tree
  • Diffuse parenchymal opacities
  • Single or multiple pulmonary nodules.
• Nodular pulmonary amyloidosis is usually found incidentally on chest radiognaphs in asymptomatic, older adults.
• The deposits originate in the muscular walls of small blood vessels, and as they enlarge, they spread into the interstitial tissues.