Pseudoxanthoma elasticum primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayokunle Olubaniyi, M.B,B.S [2]

Overview

  • Calcium restriction - This has been earlier postulated to have a positive influence on PXE by reducing the extent of mineralization.[1]
  • Combat sports are prohibited to reduce facial trauma which may lead to the development of angioid streaks and retinal hemorrhages.
  • Avoidance of risk factors for atherosclerosis such as smoking. Diabetes mellitus and hypertension should be well controlled.
  • Avoid ASA, NSAIDs, and other hypocoagulable medications that increase the risk of mucosal bleeding.

References

  1. Renie, WA.; Pyeritz, RE.; Combs, J.; Fine, SL. (1984). "Pseudoxanthoma elasticum: high calcium intake in early life correlates with severity". Am J Med Genet. 19 (2): 235–44. doi:10.1002/ajmg.1320190205. PMID 6507474. Unknown parameter |month= ignored (help)


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