Protein electrophoresis

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Schematic representation of a protein electrophoresis gel

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In chemistry and medicine, protein electrophoresis is a method of analysing a mixture of proteins by means of gel electrophoresis, mainly in blood serum (blood plasma is not suitable).

Interpretation

There are two large classes of blood proteins: serum albumin and globulin. They are generally equal in proportion, but albumin is much smaller and lightly negatively charged, leading to an accumulation of albumin on the electrophoretic gel. A small band before albumin represents transthyretin (also named prealbumin). Some forms of medication or body chemicals can cause their own band, usually small. Abnormal bands are seen in monoclonal gammopathy of undetermined significance and multiple myeloma, and are useful in the diagnosis of these conditions.

The globulins are classified by their banding pattern (with their main representatives):

See also

Cost Effectiveness of Protein electrophoresis

| group5 = Clinical Trials Involving Protein electrophoresis | list5 = Ongoing Trials on Protein electrophoresis at Clinical Trials.govTrial results on Protein electrophoresisClinical Trials on Protein electrophoresis at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Protein electrophoresis | list6 = US National Guidelines Clearinghouse on Protein electrophoresisNICE Guidance on Protein electrophoresisNHS PRODIGY GuidanceFDA on Protein electrophoresisCDC on Protein electrophoresis


| group7 = Textbook Information on Protein electrophoresis | list7 = Books and Textbook Information on Protein electrophoresis


| group8 = Pharmacology Resources on Protein electrophoresis | list8 = AND (Dose)}} Dosing of Protein electrophoresisAND (drug interactions)}} Drug interactions with Protein electrophoresisAND (side effects)}} Side effects of Protein electrophoresisAND (Allergy)}} Allergic reactions to Protein electrophoresisAND (overdose)}} Overdose information on Protein electrophoresisAND (carcinogenicity)}} Carcinogenicity information on Protein electrophoresisAND (pregnancy)}} Protein electrophoresis in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Protein electrophoresis


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Protein electrophoresis | list9 = AND (pharmacogenomics)}} Genetics of Protein electrophoresisAND (pharmacogenomics)}} Pharmacogenomics of Protein electrophoresisAND (proteomics)}} Proteomics of Protein electrophoresis


| group10 = Newstories on Protein electrophoresis | list10 = Protein electrophoresis in the newsBe alerted to news on Protein electrophoresisNews trends on Protein electrophoresis


| group11 = Commentary on Protein electrophoresis | list11 = Blogs on Protein electrophoresis

| group12 = Patient Resources on Protein electrophoresis | list12 = Patient resources on Protein electrophoresisDiscussion groups on Protein electrophoresisPatient Handouts on Protein electrophoresisDirections to Hospitals Treating Protein electrophoresisRisk calculators and risk factors for Protein electrophoresis


| group13 = Healthcare Provider Resources on Protein electrophoresis | list13 = Symptoms of Protein electrophoresisCauses & Risk Factors for Protein electrophoresisDiagnostic studies for Protein electrophoresisTreatment of Protein electrophoresis

| group14 = Continuing Medical Education (CME) Programs on Protein electrophoresis | list14 = CME Programs on Protein electrophoresis

| group15 = International Resources on Protein electrophoresis | list15 = Protein electrophoresis en EspanolProtein electrophoresis en Francais

| group16 = Business Resources on Protein electrophoresis | list16 = Protein electrophoresis in the MarketplacePatents on Protein electrophoresis

| group17 = Informatics Resources on Protein electrophoresis | list17 = List of terms related to Protein electrophoresis


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