Prostaglandin-A1 Delta-isomerase

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In enzymology, a prostaglandin-A1 Delta-isomerase (EC is an enzyme that catalyzes the chemical reaction

(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate (13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate

Hence, this enzyme has one substrate, (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate, and one product, (13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate Delta10-Delta11-isomerase. This enzyme is also called prostaglandin A isomerase.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Polet H, Levine L (1975). "Metabolism of prostaglandins E, A, and C in serum". J. Biol. Chem. 250: 351&ndash, 7. PMID 234423.

External links

The CAS registry number for this enzyme class is 9055-01-0.

Gene Ontology (GO) codes