Pranlukast

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Pranlukast
Pranlukast.png
Clinical data
Routes of
administration
Oral
ATC code
Pharmacokinetic data
MetabolismHepatic (mainly CYP3A4)[1]
Elimination half-life1.5 hours[1]
Identifiers
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC27H23N5O4
Molar mass481.503 g/mol

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List of terms related to Pranlukast

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s Singulair (montelukast).

Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

Medications of this group are normally used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. There are several similar medications in the group; all appear to be equally effective.

References

  1. 1.0 1.1 Nakade S, Ueda S, Ohno T, Nakayama K, Miyata Y, Yukawa E, Higuchi S (2006). "Population pharmacokinetics of pranlukast hydrate dry syrup in children with allergic rhinitis and bronchial asthma". Drug Metab Pharmacokinet. 21 (2): 133–9. PMID 16702733.

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