(Redirected from Polihexanide)
Jump to: navigation, search
Template:Chembox E number
Other names
Polyhexamethylene biguanide; Polyhexamethylene guanide; Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene); Poly(hexamethylenebiguanide); Polihexanide
Abbreviations PHMB
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is ☑Y☒N ?)
Infobox references

WikiDoc Resources for Polyhexanide


Most recent articles on Polyhexanide

Most cited articles on Polyhexanide

Review articles on Polyhexanide

Articles on Polyhexanide in N Eng J Med, Lancet, BMJ


Powerpoint slides on Polyhexanide

Images of Polyhexanide

Photos of Polyhexanide

Podcasts & MP3s on Polyhexanide

Videos on Polyhexanide

Evidence Based Medicine

Cochrane Collaboration on Polyhexanide

Bandolier on Polyhexanide

TRIP on Polyhexanide

Clinical Trials

Ongoing Trials on Polyhexanide at Clinical Trials.gov

Trial results on Polyhexanide

Clinical Trials on Polyhexanide at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Polyhexanide

NICE Guidance on Polyhexanide


FDA on Polyhexanide

CDC on Polyhexanide


Books on Polyhexanide


Polyhexanide in the news

Be alerted to news on Polyhexanide

News trends on Polyhexanide


Blogs on Polyhexanide


Definitions of Polyhexanide

Patient Resources / Community

Patient resources on Polyhexanide

Discussion groups on Polyhexanide

Patient Handouts on Polyhexanide

Directions to Hospitals Treating Polyhexanide

Risk calculators and risk factors for Polyhexanide

Healthcare Provider Resources

Symptoms of Polyhexanide

Causes & Risk Factors for Polyhexanide

Diagnostic studies for Polyhexanide

Treatment of Polyhexanide

Continuing Medical Education (CME)

CME Programs on Polyhexanide


Polyhexanide en Espanol

Polyhexanide en Francais


Polyhexanide in the Marketplace

Patents on Polyhexanide

Experimental / Informatics

List of terms related to Polyhexanide

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use[1] it is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, and Omnicide.[2] PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).[3]

Some products containing PHMB are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.[4]

Branded as Baquacil, it also has an application as a swimming-pool and spa water sanitizer in place of chlorine- or bromine-based products.

PHMB is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.

The PHMB hydrochloride salt (solution) is used in the majority of formulations.

See also


  1. Ansorg R, Rath PM, Fabry W (2003). "Inhibition of the anti-staphylococcal activity of the antiseptic polihexanide by mucin". Arzneimittel-Forschung. 53 (5): 368–71. doi:10.1055/s-0031-1297121. PMID 12854364.
  2. International Drug Names: Polihexanide
  3. Maribeth Cousin, Kimberly Restivo, Chelsea Rodriguez, and Justin Lien. USP Antimicrobial Effectiveness Test (GLP). Elkhorn, WI: Geneva Laboratories. 2013. http://steriwebrx.com/files/STERIWEB-FINAL-JN13J1514.pdf
  4. Nusept