Plombage
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Plombage was a surgical method used prior to the introduction of anti-tuberculosis drug therapy to treat cavitary tuberculosis of the upper lobe of the lung. The term derives from the French word "Plomb" (lead) and refers to the insertion of an inert substance in the pleural space. The technical medical term for plombage is Extraperiosteal/Extrapleural Pneumonolysis. The underlying theory of Plombage treatment was the belief that if the diseased lobe of the lung was physically forced to collapse, it would heal quickly. There were positive results in tuberculosis therapy following Plombage in the decades of the 1930s, 40s and early-50s. However, with the introduction of drugs which were effective in destroying the tuberculosis microorganism (mycobacterium tuberculosis), plombage treatment fell into disfavor. In addition, complications of plombage began to appear in patients who had been so treated. These complications included hemorrhage, infection and fistulization (abnormal opening between two hollow organs) of the bronchus, aorta, esophagus and skin. The technique involved surgically creating a cavity underneath the ribs in the upper part of the chest wall and filling this space with some inert material. A variety of substances were typically used and included air, olive or mineral oil, gauze, paraffin wax, rubber sheeting or bags and Lucite balls. The inserted material would force the upper lobe of the lung to collapse.
Cost Effectiveness of Plombage
| group5 = Clinical Trials Involving Plombage | list5 = Ongoing Trials on Plombage at Clinical Trials.gov • Trial results on Plombage • Clinical Trials on Plombage at Google
| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Plombage
| list6 = US National Guidelines Clearinghouse on Plombage • NICE Guidance on Plombage • NHS PRODIGY Guidance • FDA on Plombage • CDC on Plombage
| group7 = Textbook Information on Plombage
| list7 = Books and Textbook Information on Plombage
| group8 = Pharmacology Resources on Plombage
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AND (Dose)}} Dosing of Plombage • AND (drug interactions)}} Drug interactions with Plombage • AND (side effects)}} Side effects of Plombage • AND (Allergy)}} Allergic reactions to Plombage • AND (overdose)}} Overdose information on Plombage • AND (carcinogenicity)}} Carcinogenicity information on Plombage • AND (pregnancy)}} Plombage in pregnancy • AND (pharmacokinetics)}} Pharmacokinetics of Plombage •
| group9 = Genetics, Pharmacogenomics, and Proteinomics of Plombage
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AND (pharmacogenomics)}} Genetics of Plombage • AND (pharmacogenomics)}} Pharmacogenomics of Plombage • AND (proteomics)}} Proteomics of Plombage
| group10 = Newstories on Plombage
| list10 = Plombage in the news • Be alerted to news on Plombage • News trends on Plombage
| group11 = Commentary on Plombage
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Blogs on Plombage
| group12 = Patient Resources on Plombage | list12 = Patient resources on Plombage • Discussion groups on Plombage • Patient Handouts on Plombage • Directions to Hospitals Treating Plombage • Risk calculators and risk factors for Plombage
| group13 = Healthcare Provider Resources on Plombage
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Symptoms of Plombage • Causes & Risk Factors for Plombage • Diagnostic studies for Plombage • Treatment of Plombage
| group14 = Continuing Medical Education (CME) Programs on Plombage | list14 = CME Programs on Plombage
| group15 = International Resources on Plombage | list15 = Plombage en Espanol • Plombage en Francais
| group16 = Business Resources on Plombage | list16 = Plombage in the Marketplace • Patents on Plombage
| group17 = Informatics Resources on Plombage | list17 = List of terms related to Plombage
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