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MeSH Physalaemin
Molar mass 1265.44 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

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Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Physalaemin is a tachykinin peptide obtained from the Physalaemus frog, closely related to substance P. Its structure was first elucidated in 1964.[1][2]

Like all tachykinins, physalaemin is a sialagogue (increases salivation) and a potent vasodilator with hypotensive effects.[3]


  1. Erspaemer V, Anastasi A, Bertaccini G, Cei JM (1964). "Structure and pharmacological actions of physalaemin, the main active polypeptide of the skin of Physalaemus fuscumaculatus". Experientia. 20 (9): 489–90. PMID 5857249.
  2. Anastasi A, Erspamer V, Cei JM (1964). "Isolation and amino acid sequence of physalaemin, the main active polypeptide of the skin of Physalaemus fuscumaculatus". Arch Biochem Biophys. 108: 341–8. PMID 14240587.
  3. Severini C, Improta G, Falconieri-Erspamer G, Salvadori S, Erspamer V (2002). "The tachykinin peptide family". Pharmacol Rev. 54 (2): 285–322. PMID 12037144. Free full text

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| group5 = Clinical Trials Involving Physalaemin | list5 = Ongoing Trials on Physalaemin at Clinical Trials.govTrial results on PhysalaeminClinical Trials on Physalaemin at Google

| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Physalaemin | list6 = US National Guidelines Clearinghouse on PhysalaeminNICE Guidance on PhysalaeminNHS PRODIGY GuidanceFDA on PhysalaeminCDC on Physalaemin

| group7 = Textbook Information on Physalaemin | list7 = Books and Textbook Information on Physalaemin

| group8 = Pharmacology Resources on Physalaemin | list8 = AND (Dose)}} Dosing of PhysalaeminAND (drug interactions)}} Drug interactions with PhysalaeminAND (side effects)}} Side effects of PhysalaeminAND (Allergy)}} Allergic reactions to PhysalaeminAND (overdose)}} Overdose information on PhysalaeminAND (carcinogenicity)}} Carcinogenicity information on PhysalaeminAND (pregnancy)}} Physalaemin in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Physalaemin

| group9 = Genetics, Pharmacogenomics, and Proteinomics of Physalaemin | list9 = AND (pharmacogenomics)}} Genetics of PhysalaeminAND (pharmacogenomics)}} Pharmacogenomics of PhysalaeminAND (proteomics)}} Proteomics of Physalaemin

| group10 = Newstories on Physalaemin | list10 = Physalaemin in the newsBe alerted to news on PhysalaeminNews trends on Physalaemin

| group11 = Commentary on Physalaemin | list11 = Blogs on Physalaemin

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| group13 = Healthcare Provider Resources on Physalaemin | list13 = Symptoms of PhysalaeminCauses & Risk Factors for PhysalaeminDiagnostic studies for PhysalaeminTreatment of Physalaemin

| group14 = Continuing Medical Education (CME) Programs on Physalaemin | list14 = CME Programs on Physalaemin

| group15 = International Resources on Physalaemin | list15 = Physalaemin en EspanolPhysalaemin en Francais

| group16 = Business Resources on Physalaemin | list16 = Physalaemin in the MarketplacePatents on Physalaemin

| group17 = Informatics Resources on Physalaemin | list17 = List of terms related to Physalaemin