Perfusion weighted imaging

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MR Perfusion

Perfusion weighted imaging or MR perfusion is a term used to denote a variety of MRI techniques able to give insights into the perfusion of tissues by blood.


There are three techniques in wide use to derive one or more perfusion values.

  • Dynamic susceptibility contrast imaging (DSC)
  • Dynamic contrast enhanced imaging (DCE)
  • Arterial spin labelled imaging (ASL)

Derived values

  • Time to peak (TTP)
  • Mean transit time (MTT)
  • Cerebral blood volume (CBV)
  • Cerebral blood flow (CBF)
  • Negative enhancement integral (NEI)
  • K-trans

The main role of perfusion imaging is in evaluation of ischemic conditions (e.g. acute cerebral infarction to determine ischemic penumbra, moya-moya disease to identify vascular reserve) and neoplasms (e.g. identify highest grade component of diffuse astrocytomas, help distinguish glioblastomas form cerebral metastases).