Pancreatic fistula medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Treatment of pancreatic fistula includes early recognition of the problem which is the key to careful management in order to prevent the consequent complications. Medical therapy is tailored towards the suppression of pancreatic enzymes by restricting the patient's oral intake of food in conjunction with the use of long-acting somatostatin analogues such as octreotide. Correction of the fluid and electrolyte abnormalities. The patient's nutrition is maintained by total parenteral nutrition. This treatment is continued for 2-3 weeks, and the patient is observed for improvement.
Medical Therapy
Treatment of pancreatic fistula includes early recognition of the problem which is the key to careful management in order to prevent the consequent complications.
- Medical therapy is tailored towards the suppression of pancreatic enzymes by restricting the patient's oral intake of food in conjunction with the use of long-acting somatostatin analogues such as octreotide.[1] Octreotide is used commonly to control pancreatic secretion, however, no significant benefit is observed with its use in patients with already established pancreatic fistula.[2]
- Correction of the electrolyte disturbances.
- The patient's nutrition is maintained by total parenteral nutrition to reduce pancreatic stimulation. This treatment is continued for 2-3 weeks, and the patient is observed for improvement.[3]
References
- ↑ Takeo C, Myojo S (2000). "Marked effect of octreotide acetate in a case of pancreatic pleural effusion". Curr Med Res Opin. 16 (3): 171–7. PMID 11191006.
- ↑ "StatPearls". 2021. PMID 32809706 Check
|pmid=value (help). - ↑ Nahm CB, Connor SJ, Samra JS, Mittal A (2018). "Postoperative pancreatic fistula: a review of traditional and emerging concepts". Clin Exp Gastroenterol. 11: 105–118. doi:10.2147/CEG.S120217. PMC 5858541. PMID 29588609.