DNA-directed RNA polymerase III subunit RPC4 is an enzyme that in humans is encoded by the POLR3Dgene.[1][2][3]
This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures.[3]
↑Chong SS, Hu P, Hernandez N (Jun 2001). "Reconstitution of transcription from the human U6 small nuclear RNA promoter with eight recombinant polypeptides and a partially purified RNA polymerase III complex". J Biol Chem. 276 (23): 20727–34. doi:10.1074/jbc.M100088200. PMID11279001.
Jang KL, Collins MK, Latchman DS (1992). "The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC". J. Acquir. Immune Defic. Syndr. 5 (11): 1142–7. PMID1403646.
Greco A, Ittmann M, Barletta C, et al. (1989). "Chromosomal localization of human genes required for G1 progression in mammalian cells". Genomics. 4 (3): 240–5. doi:10.1016/0888-7543(89)90326-1. PMID2714790.
Ittmann MM (1994). "Cell cycle control of the BN51 cell cycle gene which encodes a subunit of RNA polymerase III". Cell Growth Differ. 5 (7): 783–8. PMID7947392.
