POLM

Polymerase (DNA directed), mu
File:PBB Protein POLM image.jpg PDB rendering based on 2dun.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2dun​, 2htf​
Identifiers
Symbols	POLM ; Tdt-N
External IDs	Template:OMIM5 Template:MGI HomoloGene: 41170
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE POLM 222238 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Polymerase (DNA directed), mu, also known as POLM, is a human gene.

Further reading

• Shimazaki N, Fujita K, Koiwai O (2002). "[Expression and function of terminal deoxynucleotidyl-transferase and discovery of novel DNA polymerase mu]". Seikagaku. 74 (3): 227–32. PMID 11974916.CS1 maint: Multiple names: authors list (link)
• Domínguez O, Ruiz JF, Laín de Lera T; et al. (2000). "DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells". EMBO J. 19 (7): 1731–42. doi:10.1093/emboj/19.7.1731. PMID 10747040.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Aoufouchi S, Flatter E, Dahan A; et al. (2000). "Two novel human and mouse DNA polymerases of the polX family". Nucleic Acids Res. 28 (18): 3684–93. PMID 10982892.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Haracska L, Johnson RE, Unk I; et al. (2002). "Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA". Proc. Natl. Acad. Sci. U.S.A. 98 (25): 14256–61. doi:10.1073/pnas.261560798. PMID 11724965.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Duvauchelle JB, Blanco L, Fuchs RP, Cordonnier AM (2002). "Human DNA polymerase mu (Pol mu) exhibits an unusual replication slippage ability at AAF lesion". Nucleic Acids Res. 30 (9): 2061–7. PMID 11972346.CS1 maint: Multiple names: authors list (link)
• Mahajan KN, Nick McElhinny SA, Mitchell BS, Ramsden DA (2002). "Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair". Mol. Cell. Biol. 22 (14): 5194–202. PMID 12077346.CS1 maint: Multiple names: authors list (link)
• Zhang Y, Wu X, Guo D; et al. (2003). "Lesion bypass activities of human DNA polymerase mu". J. Biol. Chem. 277 (46): 44582–7. doi:10.1074/jbc.M207297200. PMID 12228225.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chiu A, Pan L, Li Z; et al. (2002). "DNA polymerase mu gene expression in B-cell non-Hodgkin's lymphomas: an analysis utilizing in situ hybridization". Am. J. Pathol. 161 (4): 1349–55. PMID 12368208.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nick McElhinny SA, Ramsden DA (2003). "Polymerase mu is a DNA-directed DNA/RNA polymerase". Mol. Cell. Biol. 23 (7): 2309–15. PMID 12640116.
• Covo S, Blanco L, Livneh Z (2004). "Lesion bypass by human DNA polymerase mu reveals a template-dependent, sequence-independent nucleotidyl transferase activity". J. Biol. Chem. 279 (2): 859–65. doi:10.1074/jbc.M310447200. PMID 14581466.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Washington MT, Minko IG, Johnson RE; et al. (2004). "Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa". Mol. Cell. Biol. 24 (13): 5687–93. doi:10.1128/MCB.24.13.5687-5693.2004. PMID 15199127.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Roettger MP, Fiala KA, Sompalli S; et al. (2004). "Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu". Biochemistry. 43 (43): 13827–38. doi:10.1021/bi048782m. PMID 15504045.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ruiz JF, Lucas D, García-Palomero E; et al. (2004). "Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate". Nucleic Acids Res. 32 (19): 5861–73. doi:10.1093/nar/gkh929. PMID 15520469.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nick McElhinny SA, Havener JM, Garcia-Diaz M; et al. (2005). "A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining". Mol. Cell. 19 (3): 357–66. doi:10.1016/j.molcel.2005.06.012. PMID 16061182.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Juárez R, Ruiz JF, Nick McElhinny SA; et al. (2006). "A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis". Nucleic Acids Res. 34 (16): 4572–82. doi:10.1093/nar/gkl457. PMID 16963491.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)