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Osazones are a class of carbohydrate derivatives found in organic chemistry formed when sugars are reacted with phenylhydrazine. The famous German chemist Emil Fischer developed and used the reaction to identify sugars whose stereochemistry differed by only one chiral carbon. The reaction involves formation of a pair of phenylhydrazone functionalities, concomitant with the oxidation of the hydroxymethylene group adjacent to the formyl center. The reaction can be used to identify sugars.

A general reaction showing the formation of an osazone. D-glucose reacts with phenylhydrazine to give glucose osazone. The same product is obtained from mannose