Nodular fasciitis

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Nodular fasciitis
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Histopathology of nodular fasciitis found in forearm. H&E stain.
ICD-10 M72.4
ICD-9 728.79

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and Keywords: Nodular pseudosarcomatous fasciits; subcutaneous pseudosarcomatous fibromatosis

Overview

Nodular fasciitis, also known as Nodular pseudosarcomatous fasciits and Subcutaneous pseudosarcomatous fibromatosis[1]:992, is a benign[2] lesion most commonly found in the superficial fascia. It is most common in young persons on the upper extremities and trunk. Commonly mistaken for a sarcoma.

Pathophysiology

Histology

  • Histologically vast array of patterns.
  • Short S-shaped fascicles, inflammation, accelerated mitotic index with normal mitoses.
  • Essentially spindle cell proliferation.
  • Stroma is rich in collagen and/or myxoid ground substance.

Natural History and Prognosis

Similar to a dermatofibroma, it is believed to be a reparative process secondary to trauma, which is frequently not remembered. It evolves rapidly, but is usually less than 3 cm in diameter. There is an extremely low incidence of recurrence after resection.

References

  1. Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
  2. Sailon AM, Cappuccino G, Hameed M, Fleegler EJ (2008). "Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report". Eplasty. 8: e38. PMC 2491338. PMID 18725954.

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