Nisoxetine

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Nisoxetine
File:Nisoxetine.svg
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC17H21NO2
Molar mass271.354 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Nisoxetine (LY-94939) is a drug which inhibits the reuptake of norepinephrine (noradrenaline). It is a racemic compound with two isomers.

Uses

Nisoxetine is not currently used in humans,[1] but was originally researched as an antidepressant and is now widely used in scientific research as a standard selective noradrenaline reuptake inhibitor.[2]

References

  1. Kelwala S, Stanley M, Gershon S. History of antidepressants: successes and failures. Journal of Clinical Psychiatry. 1983 May;44(5 Pt 2):40-8.PMID 6222036
  2. Graham D, Langer SZ. Advances in sodium-ion coupled biogenic amine transporters. Life Sciences. 1992;51(9):631-45.PMID 1501510



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