|YOMESAN® Package Insert|
It is stressed that while anthelmintics are a drug familiy used to treat worm infections, Niclosamide is used specifically to treat tapeworms and is not effective against worms such as pinworms or roundworms.
It is a chewable tablet taken orally, dosage depending on type of worm and patient's age and/or weight.
Niclosamide molecules are lethal to tapeworms upon contact.
US Brand Names
NICLOCIDE®, YOMESAN® (DISCONTINUED)
FDA Package Insert
Mechanism of Action
Niclosamide uncouples oxidative phosphorylation in the tapeworm.
- Weinbach EC, Garbus J (1969). "Mechanism of action of reagents that uncouple oxidative phosphorylation". Nature. 221 (5185): 1016–8.