Myocardial rupture pathophysiology

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Myocardial rupture Microchapters


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Epidemiology and Demographics

Risk Factors

Relative Contribution of Myocardial Rupture as a Cause of Sudden Cardiac Death Following STEMI

Natural History, Complications and Prognosis


History and Symptoms

Physical Examination


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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]


The most common cause of myocardial rupture is a recent myocardial infarction, with the rupture typically occurring three to five days after infarction. Other causes of rupture include cardiac trauma, endocarditis (infection of the heart),[1][2] cardiac tumors, infiltrative diseases of the heart,[1] and aortic dissection.


Images shown below are courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

Myocardial Rupture of the Free Wall

Ventricular Septal Rupture


  1. 1.0 1.1 Lin TH, Su HM, Voon WC, Lai HM, Yen HW, Lai WT, Sheu SH. (2006). "Association between hypertension and primary mitral chordae tendinae rupture". Am J Hypertens. 19 (1): 75–9. PMID 16461195.
  2. de Diego C, Marcos-Alberca P, Pai RK. (2006). "Giant periprosthetic vegetation associated with pseudoaneurysmal-like rupture" (PDF). Eur Heart J. 27 (8): 912. PMID 16569654.

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