Mycobacterium haemophilum

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Mycobacterium haemophilum
Scientific classification
Kingdom: Bacteria
Phylum: Actinobacteria
Order: Actinomycetales
Suborder: Corynebacterineae
Family: Mycobacteriaceae
Genus: Mycobacterium
Species: M. haemophilum
Binomial name
Mycobacterium haemophilum
Sompolinsky et al. 1978, ATCC 29548

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Mycobacterium haemophilum


Short, occasionally curved, gram-positive, nonmotile and strongly acid-fast rods.

Colony characteristics

  • Nonpigmented and rough to smooth colonies.


  • Media have to be supplemented with 0.4% haemoglobin or 60µM hemin (factor X) or 15mg/ml ferric ammonium citrate respectively, but not with FeCl3 or catalase.
  • Slow growth on Löwenstein-Jensen media or Middlebrook 7H10 agar at 32°C within 2-4 weeks.
  • Growth slower at 25°C and 35°C and absent at 37°C.
  • Strictly intracellular growth in tissue cultures of fibroblasts.

Differential characteristics

  • Unique among mycobacteria in its requirement for hemin or ferric ammonium citrate for growth.



Type Strain

First isolated in Israel from a subcutaneous granuloma from a patient with Hodgkin's disease. An environmental reservoir is presumed. Strain ATCC 29548 = CCUG 47452 = CIP 105049 = DSM 44634 = NCTC 11185.


Antimicrobial regimen

  • 1. In vitro [1]
  • 2. Disseminated disease


  1. Griffith, David E.; Aksamit, Timothy; Brown-Elliott, Barbara A.; Catanzaro, Antonino; Daley, Charles; Gordin, Fred; Holland, Steven M.; Horsburgh, Robert; Huitt, Gwen; Iademarco, Michael F.; Iseman, Michael; Olivier, Kenneth; Ruoss, Stephen; von Reyn, C. Fordham; Wallace, Richard J.; Winthrop, Kevin; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America (2007-02-15). "An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases". American Journal of Respiratory and Critical Care Medicine. 175 (4): 367–416. doi:10.1164/rccm.200604-571ST. ISSN 1073-449X. PMID 17277290.
  • Sompolinsky et al. 1978. Mycobacterium haemophilum sp. nov., a new pathogen of humans. International Journal of Systematic Bacteriology, 28, 67-75.

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