Moricizine (patient information)

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IMPORTANT WARNING

Some antiarrhythmic drugs may increase the risk of death. It is not known whether people with irregular heartbeats who take moricizine live longer than those who do not take moricizine. Tell your doctor if you have had a heart attack within the past two years.

Moricizine should be used only to treat life-threatening arrhythmias (irregular heartbeats). Talk to your doctor about the risk of taking moricizine.

Why this medication is prescribed

Moricizine is used to treat irregular heartbeats (arrhythmias) and to maintain a normal heart rate. It acts on the heart muscle to improve the heart's rhythm.

How this medication should be used

Moricizine comes as a tablet to take by mouth. It usually is taken every 8 hours. This medication is sometimes started in the hospital where your response can be monitored. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take moricizine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Moricizine controls irregular heartbeats, but does not cure them. Continue to take moricizine even if you feel well. Do not stop taking moricizine without talking to your doctor. Your heartbeats may become irregular if you suddenly stop taking moricizine.

Other uses for this medicine

This medication should not be prescribed for other uses; ask your doctor or pharmacist for more information.

Special precautions

Before taking moricizine:

  • tell your doctor and pharmacist if you are allergic to moricizine or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cimetidine (Tagamet), digoxin (Lanoxin), propranolol (Inderal), theophylline (Theo-Dur), and vitamins
  • in addition to the condition in the IMPORTANT WARNING section, tell your doctor if you have or have ever had liver or kidney disease, congestive heart failure, or a pacemaker.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking moricizine, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking moricizine.
  • you should know that this drug may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how it affects you.

Special dietary instructions

Talk to your doctor about your diet. Foods and salt substitutes containing potassium can affect the action of moricizine.

What to do if you forget a dose

Take the missed dose if you remember it within 4 hours. If you do not remember it until 4 or more hours after the scheduled time, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Side Effects

Minor Side Effects

Moricizine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • upset stomach
  • dizziness
  • nervousness
  • difficult urination
  • blurred vision
  • headache
  • diarrhea
  • vomiting
  • gas

Severe Side Effects

If you experience any of the following symptoms, call your doctor immediately:

  • difficulty breathing
  • chest pain
  • irregular heartbeats
  • increased or decreased heartbeat
  • fainting
  • skin rash
  • swollen feet or ankles
  • unexplained fever

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

Storage conditions needed for this medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Other information

Keep all appointments with your doctor and the laboratory. Your doctor may want to evaluate the effectiveness of moricizine with physical examinations, EKG (electrocardiogram) tests, and blood tests.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names

  • Ethmozine®

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