Mononucleosis primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Majority of mononucleosis syndromes are caused by Epstein-Barr virus, and most people become infected with EBV sometime during their lives with an estimated 90-95% population aged more than 21 years demonstrate antibody to EBV.[1][2] The transmission of the virus requires intimate contact with the saliva of an infected person and rarely occurs via air or blood. Therefore, the most reasonable way to prevent mono is to avoid close contact with infected saliva.


  1. Henle G, Henle W, Clifford P, Diehl V, Kafuko GW, Kirya BG, Klein G, Morrow RH, Munube GM, Pike P, Tukei PM, Ziegler JL (1969). "Antibodies to Epstein-Barr virus in Burkitt's lymphoma and control groups". Journal of the National Cancer Institute. 43 (5): 1147–57. PMID 5353242. Unknown parameter |month= ignored (help); |access-date= requires |url= (help)
  2. Pereira MS, Blake JM, Macrae AD (1969). "EB virus antibody at different ages". British Medical Journal. 4 (5682): 526–7. PMC 1630375. PMID 4902364. Unknown parameter |month= ignored (help); |access-date= requires |url= (help)

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