Migraine secondary prevention

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Melatonin might be helpful for prophylaxis of migraine headaches according to randomized controlled trial.[1]

References

  1. Gonçalves AL, Martini Ferreira A, Ribeiro RT, Zukerman E, Cipolla-Neto J, Peres MF (2016). "Randomised clinical trial comparing melatonin 3 mg, amitriptyline 25 mg and placebo for migraine prevention". J Neurol Neurosurg Psychiatry. doi:10.1136/jnnp-2016-313458. PMID 27165014.