Methoxamine

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Methoxamine
Systematic (IUPAC) name
 ?
Identifiers
CAS number 390-28-3
ATC code C01CA10
PubChem 6082
Chemical data
Formula C11H17NO3 
Mol. mass 211.258
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

WikiDoc Resources for Methoxamine

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Methoxamine is an α1-adrenergic receptor agonist,[1] similar in structure to phenylephrine and 2,5-DMA. It was developed by Burroughs-Wellcome in the 1940s.[2] The drug induces vasoconstriction of skin and splanchnic blood vessels, thereby increasing peripheral vascular resistance and raising mean arterial blood pressure. Because of its hypertensive effects, it may evoke a compensatory reflex bradycardia via the baroreceptors.

See Also

References

  1. Pazdernik, Thomas L.; Kerecsen, Laszlo (2007) [2003]. "5". In Goljan, Edward F. Pharmacology (Paperback). Rapid Review (Second ed.). Philadelphia, PA: Mosby-Elsevier. p. 39. ISBN 978-0-323-04550-6. 
  2. US Patent 2359707 - DIMETHOXYPHENYL beta-HYDROXY ISOPROPYLAMINE

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