Mantle cell lymphoma other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ali Akram, M.B.B.S.[2] Sowminya Arikapudi, M.B,B.S. [3]

Overview

Other diagnostic studies for the diagnosis of mantle cell lymphoma include bone marrow aspiration, lumbar puncture, colonoscopy, upper endoscopy, laparoscopy, and laparotomy.

Other Diagnostic Studies

Other diagnostic studies for the diagnosis of mantle cell lymphoma include:

Bone Marrow Aspiration

Mantle cell lymphoma is a systemic disease that can affect the extra nodal sites like the bone marrow and the peripheral blood. Therefore, bone marrow biopsy is useful in the diagnosis of MCL.[1]

Lumbar Puncture

In some patients with the blastic variant, lumbar puncture is done to evaluate the spinal fluid for CNS involvement.[2]

Colonoscopy

Lymphomatous polyposis coli and colon involvement is common in MCL, so, colonoscopy can be helpful in the diagnosis of MCL.[3]

Upper Endoscopy

Upper endoscopy may be helpful in selected cases involving the gastrointestinal tract.

References

  1. Daniel A. Arber & Tracy I. George (2005). "Bone marrow biopsy involvement by non-Hodgkin's lymphoma: frequency of lymphoma types, patterns, blood involvement, and discordance with other sites in 450 specimens". The American journal of surgical pathology. 29 (12): 1549–1557. PMID 16327427. Unknown parameter |month= ignored (help)
  2. https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf
  3. https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf

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