Malate dehydrogenase (decarboxylating)
- (S)-malate + NAD+ pyruvate + CO2 + NADH
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-malate:NAD+ oxidoreductase (decarboxylating). Other names in common use include 'malic' enzyme, pyruvic-malic carboxylase, NAD+-specific malic enzyme, and NAD+-malic enzyme. This enzyme participates in pyruvate metabolism and carbon fixation.
- IUBMB entry for 18.104.22.168
- BRENDA references for 22.214.171.124 (Recommended.)
- PubMed references for 126.96.36.199
- PubMed Central references for 188.8.131.52
- Google Scholar references for 184.108.40.206
- Saz HJ and Hubbard JA (1957). "The oxidative decarboxylation of malate by Ascoris lumbricoides". J. Biol. Chem. 225: 921&ndash, 933.
- The CAS registry number for this enzyme class is 9028-46-0.
Gene Ontology (GO) codes
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