MAGEC2

This article is about the protein. For other uses, see Magec (disambiguation).

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Species	Human	Mouse
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Wikidata
View/Edit Human

Melanoma-associated antigen C2 is a protein that in humans is encoded by the MAGEC2 gene.

This gene is related to members of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and the MAGEC genes are clustered on chromosome Xq26-q27.

Further reading

• Lucas S, De Plaen E, Boon T (2000). "MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression". Int. J. Cancer. 87 (1): 55–60. doi:10.1002/1097-0215(20000701)87:1<55::AID-IJC8>3.0.CO;2-J. PMID 10861452.
• Sasaki M, Nakahira K, Kawano Y, et al. (2001). "MAGE-E1, a new member of the melanoma-associated antigen gene family and its expression in human glioma". Cancer Res. 61 (12): 4809–14. PMID 11406556.
• Kawano Y, Sasaki M, Nakahira K, et al. (2001). "Structural characterization and chromosomal localization of the MAGE-E1 gene". Gene. 277 (1–2): 129–37. doi:10.1016/S0378-1119(01)00698-9. PMID 11602350.
• Wang Y, Han KJ, Pang XW, et al. (2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. 169 (2): 1102–9. doi:10.4049/jimmunol.169.2.1102. PMID 12097419.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Li B, Qian XP, Pang XW, et al. (2003). "HCA587 antigen expression in normal tissues and cancers: correlation with tumor differentiation in hepatocellular carcinoma". Lab. Invest. 83 (8): 1185–92. doi:10.1097/01.LAB.0000080605.73839.96. PMID 12920247.
• Ma W, Germeau C, Vigneron N, et al. (2004). "Two new tumor-specific antigenic peptides encoded by gene MAGE-C2 and presented to cytolytic T lymphocytes by HLA-A2". Int. J. Cancer. 109 (5): 698–702. doi:10.1002/ijc.20038. PMID 14999777.
• Wang Y, Liang Z, Yuan YH, et al. (2004). "[Expression of multiple cancer-testis antigen genes in non-small cell lung cancer treated by chemotherapy prior surgery]". Zhonghua Yi Xue Za Zhi. 84 (6): 464–8. PMID 15061963.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Godelaine D, Carrasco J, Brasseur F, et al. (2007). "A new tumor-specific antigen encoded by MAGE-C2 and presented to cytolytic T lymphocytes by HLA-B44". Cancer Immunol. Immunother. 56 (6): 753–9. doi:10.1007/s00262-006-0244-5. PMID 17096150.
• Yang B, Wu J, Maddodi N, et al. (2007). "Epigenetic control of MAGE gene expression by the KIT tyrosine kinase". J. Invest. Dermatol. 127 (9): 2123–8. doi:10.1038/sj.jid.5700836. PMID 17495964.