LOC4951

Oncomodulin
File:PBB Protein OCM image.jpg PDB rendering based on 1omd.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1omd​, 1rro​, 1ttx​
Identifiers
Symbols	OCM ; OM; ONCM; LOC654231
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4511
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Oncomodulin, also known as OCM, is a human gene.

Oncomodulin is a high-affinity calcium ion-binding protein. It belongs to the superfamily of calmodulin proteins, also known as the EF-hand proteins. Oncomodulin is an oncodevelopmental protein found in early embryonic cells in the placenta and also in tumors.

Further reading

• Pauls TL, Cox JA, Berchtold MW (1996). "The Ca2+(-)binding proteins parvalbumin and oncomodulin and their genes: new structural and functional findings". Biochim. Biophys. Acta. 1306 (1): 39–54. PMID 8611623.CS1 maint: Multiple names: authors list (link)
• Belkacemi L, Simoneau L, Lafond J (2003). "Calcium-binding proteins: distribution and implication in mammalian placenta". Endocrine. 19 (1): 57–64. PMID 12583602.CS1 maint: Multiple names: authors list (link)
• Ritzler JM, Sawhney R, Geurts van Kessel AH; et al. (1992). "The genes for the highly homologous Ca(2+)-binding proteins oncomodulin and parvalbumin are not linked in the human genome". Genomics. 12 (3): 567–72. PMID 1559707.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Palmer EJ, MacManus JP, Mutus B (1990). "Inhibition of glutathione reductase by oncomodulin". Arch. Biochem. Biophys. 277 (1): 149–54. PMID 2306116.CS1 maint: Multiple names: authors list (link)
• Mutus B, Palmer EJ, MacManus JP (1988). "Disulfide-linked dimer of oncomodulin: comparison to calmodulin". Biochemistry. 27 (15): 5615–22. PMID 3179268.CS1 maint: Multiple names: authors list (link)
• Gillen MF, Banville D, Rutledge RG; et al. (1987). "A complete complementary DNA for the oncodevelopmental calcium-binding protein, oncomodulin". J. Biol. Chem. 262 (11): 5308–12. PMID 3558395.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• MacManus JP, Brewer LM, Whitfield JF (1985). "The widely-distributed tumour protein, oncomodulin, is a normal constituent of human and rodent placentas". Cancer Lett. 27 (2): 145–51. PMID 4005827.CS1 maint: Multiple names: authors list (link)
• Blum JK, Berchtold MW (1994). "Calmodulin-like effect of oncomodulin on cell proliferation". J. Cell. Physiol. 160 (3): 455–62. doi:10.1002/jcp.1041600308. PMID 8077283.
• Föhr UG, Weber BR, Müntener M; et al. (1993). "Human alpha and beta parvalbumins. Structure and tissue-specific expression". Eur. J. Biochem. 215 (3): 719–27. PMID 8354278.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sakaguchi N, Henzl MT, Thalmann I; et al. (2000). "Oncomodulin is expressed exclusively by outer hair cells in the organ of Corti". J. Histochem. Cytochem. 46 (1): 29–40. PMID 9405492.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. PMID 9847074.
• Harrington JJ, Sherf B, Rundlett S; et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hillier LW, Fulton RS, Fulton LA; et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Babini E, Bertini I, Capozzi F; et al. (2005). "Solution structure of human beta-parvalbumin and structural comparison with its paralog alpha-parvalbumin and with their rat orthologs". Biochemistry. 43 (51): 16076–85. doi:10.1021/bi048388o. PMID 15610002.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)