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File:Nuclear changes.jpg
Morphological characteristics of karyolysis and other forms of nuclear destruction

Karyolysis is the complete dissolution of the chromatin matter of a dying cell due to the activity of DNAase. The whole cell will eventually stain uniformly with eosin after karyolysis. It is usually preceded by karyorrhexis and can occur either as a result of programmed cell death or necrosis.

See also