Hyper-IgM syndrome type 3
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| Hyper-IgM syndrome type 3 | |
| Immunoglobulin M | |
| ICD-10 | D80.5 |
| ICD-9 | 279.05 |
| OMIM | 606843 |
| eMedicine | ped/2457 |
| MeSH | D053306 |
Hyper-IgM syndrome type 3 is a form of Hyper IgM syndrome characterized by mutations of the CD40 gene. In this type, B cells cannot receive the signal from T cells to switch classes.