Humoral immune deficiency

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Humoral immune deficiency
Original antigenic sin.png
B cells and antibody
ICD-10 D80
ICD-9 279.0

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and Keywords: B cell deficiency

Overview

Humoral immune deficiencies are conditions which cause impairment of humoral immunity, which can lead to immunodeficiency. It can be mediated by failures of B cells, the plasma cells they differentiate into, or the antibody secreted by the plasma cells.

They are associated with increased vulnerability to infection, but can be difficult to detect (or asymptomatic) in the absence of infection.

They can be associated with increased risk of gastric cancer.[1]

References

  1. den Hartog G, Jansen JB, van der Meer JW, Lamers CB (1992). "Gastric abnormalities in humoral immune deficiency syndromes". Scand. J. Gastroenterol. Suppl. 194: 38–40. PMID 1298045.

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