Howell-Jolly body

(Redirected from Howell-Jolly bodies)
Jump to navigation Jump to search

WikiDoc Resources for Howell-Jolly body

Articles

Most recent articles on Howell-Jolly body

Most cited articles on Howell-Jolly body

Review articles on Howell-Jolly body

Articles on Howell-Jolly body in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Howell-Jolly body

Images of Howell-Jolly body

Photos of Howell-Jolly body

Podcasts & MP3s on Howell-Jolly body

Videos on Howell-Jolly body

Evidence Based Medicine

Cochrane Collaboration on Howell-Jolly body

Bandolier on Howell-Jolly body

TRIP on Howell-Jolly body

Clinical Trials

Ongoing Trials on Howell-Jolly body at Clinical Trials.gov

Trial results on Howell-Jolly body

Clinical Trials on Howell-Jolly body at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Howell-Jolly body

NICE Guidance on Howell-Jolly body

NHS PRODIGY Guidance

FDA on Howell-Jolly body

CDC on Howell-Jolly body

Books

Books on Howell-Jolly body

News

Howell-Jolly body in the news

Be alerted to news on Howell-Jolly body

News trends on Howell-Jolly body

Commentary

Blogs on Howell-Jolly body

Definitions

Definitions of Howell-Jolly body

Patient Resources / Community

Patient resources on Howell-Jolly body

Discussion groups on Howell-Jolly body

Patient Handouts on Howell-Jolly body

Directions to Hospitals Treating Howell-Jolly body

Risk calculators and risk factors for Howell-Jolly body

Healthcare Provider Resources

Symptoms of Howell-Jolly body

Causes & Risk Factors for Howell-Jolly body

Diagnostic studies for Howell-Jolly body

Treatment of Howell-Jolly body

Continuing Medical Education (CME)

CME Programs on Howell-Jolly body

International

Howell-Jolly body en Espanol

Howell-Jolly body en Francais

Business

Howell-Jolly body in the Marketplace

Patents on Howell-Jolly body

Experimental / Informatics

List of terms related to Howell-Jolly body

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Howell-Jolly bodies are histopathological findings of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. During maturation in the bone marrow erythrocytes normally expel their nuclei, but in some cases a small portion of DNA remains. This DNA appears as a basophilic (purple) spot on the otherwise eosinophilic (pink) erythrocyte on a standard H and E stained blood smear. These inclusions are normally pitted out by the spleen during erythrocyte circulation, but will persist in individuals with functional hyposplenia or asplenia. Common causes of asplenia are splenectomy due to trauma, and autosplenectomy caused by sickle cell anemia. Other causes are radiation therapy involving the spleen, such as that used to treat Hodgkin lymphoma.

Howell-Jolly bodies are also seen in severe hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, and myelodysplastic syndrome (MDS).

Diagnosis

Pathology

Howel Jolly Bodies (Asplenia) [1]

External links


de:Howell-Jolly-Körperchen


Template:WikiDoc Sources