HIV associated nephropathy diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2];Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[3]Krzysztof Wierzbicki M.D. [4]
Overview
Renal biopsy is the diagnostic study of choice for HIV-associated nephropathy (HIVAN). Renal biopsy reveals the following findings: collapsing focal segmental glomerulonephritis, significant tubulointerstitial injury, interstitial fibrosis and inflammation and microcystic tubular dilation.
HIV associated nephropathy Diagnostic Study of Choice
Renal Biopsy
- Renal biopsy is the diagnostic study of choice for HIV-associated nephropathy (HIVAN).
- Renal biopsy is an essential tool for evaluation and identification of HIV-associated and other kidney diseases in HIV-positive patients, which is important in the management and treatment of the patients.[1]
- Renal biopsy reveals the following findings in HIVAN:[2]
- Collapsing focal segmental glomerulonephritis
- Significant tubulointerstitial injury
- Interstitial fibrosis and inflammation
- Microcystic tubular dilation
References
- ↑ Fine DM, Perazella MA, Lucas GM, Atta MG (2008). "Kidney biopsy in HIV: beyond HIV-associated nephropathy". Am J Kidney Dis. 51 (3): 504–14. doi:10.1053/j.ajkd.2007.12.005. PMID 18295067.
- ↑ D'Agati V, Suh JI, Carbone L, Cheng JT, Appel G (1989). "Pathology of HIV-associated nephropathy: a detailed morphologic and comparative study". Kidney Int. 35 (6): 1358–70. PMID 2770114.