In emergency medicine, a GI cocktail (gastrointestinal cocktail) is a generic term for a mixture of liquid antacid, viscous lidocaine, and an anticholinergic to treat dyspepsia.
A common type includes a mixtures of Maalox, Donnatal, and Xylocaine in equal parts. The theory is since these all work by different mechanisms, the mixture will be more effective than just one.
Many different combinations of GI cocktails are used, however, there is much dispute in recent research as to what is the best approach. Some researchers have found that many GI cocktails may not be as effective as one antacid.